Overexpression, purification, and partial characterization of ADP-ribosyltransferases modA and modB of bacteriophage T4.

Abstract

There is increasing experimental evidence that ADP-ribosylation of host proteins is an important means to regulate gene expression of bacteriophage T4. Surprisingly, this phage codes for three different ADP-ribosyltransferases, gene products Alt, ModA, and ModB, modifying partially overlapping sets of host proteins. While gene product Alt already has been… (More)

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