Overexpressed CacyBP/SIP leads to the suppression of growth in renal cell carcinoma.

@article{Sun2007OverexpressedCL,
  title={Overexpressed CacyBP/SIP leads to the suppression of growth in renal cell carcinoma.},
  author={Shiren Sun and Xiaoxuan Ning and Jie Liu and Lili Liu and Yu Chen and Shuang Han and Yanqi Zhang and Jie Liang and Kaichun Wu and Dai-ming Fan},
  journal={Biochemical and biophysical research communications},
  year={2007},
  volume={356 4},
  pages={864-71}
}
Calcyclin-binding protein/Siah-1-interacting protein (CacyBP/SIP), a target protein of S100, has been identified as a component of a novel ubiquitinylation complex leading to beta-catenin degradation, which was found to be related to the malignant phenotypes of gastric cancer. However, the roles of CacyBP/SIP in renal cell carcinoma still remain unclear. In the present study, we had analyzed the expression of the CacyBP/SIP protein in human renal cancer cells and clinical tissue samples. The… CONTINUE READING