Overdispersion of the molecular clock varies between yeast, Drosophila and mammals.

@article{Bedford2008OverdispersionOT,
  title={Overdispersion of the molecular clock varies between yeast, Drosophila and mammals.},
  author={Trevor B. C. Bedford and Ilan Wapinski and Daniel L. Hartl},
  journal={Genetics},
  year={2008},
  volume={179 2},
  pages={977-84}
}
Although protein evolution can be approximated as a "molecular evolutionary clock," it is well known that sequence change departs from a clock-like Poisson expectation. Through studying the deviations from a molecular clock, insight can be gained into the forces shaping evolution at the level of proteins. Generally, substitution patterns that show greater variance than the Poisson expectation are said to be "overdispersed." Overdispersion of sequence change may result from temporal variation in… CONTINUE READING

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