Overcoming remyelination failure in multiple sclerosis and other myelin disorders.

  title={Overcoming remyelination failure in multiple sclerosis and other myelin disorders.},
  author={Stephen P J Fancy and Mark Kotter and Emily P. Harrington and Jeffrey K Huang and Chao Zhao and David H Rowitch and Robin J. M. Franklin},
  journal={Experimental neurology},
  volume={225 1},
Protecting axons from degeneration represents a major unmet need in the treatment of myelin disorders and especially the currently untreatable secondary progressive stages of multiple sclerosis (MS). Several lines of evidence indicate that ensuring myelin sheaths are restored to demyelinated axons, the regenerative process of remyelination, represents one of the most effective means of achieving axonal protection. Remyelination can occur as a highly effective spontaneous regenerative process… CONTINUE READING
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Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis

  • P. M. Matthews, S. L. Hauser, L. Kappos, C. H. Polman, J. R. Oksenberg
  • Hum. Mol. Genet
  • 2009

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