Overcoming Challenges in Engineering Large, Scaffold-Free Neocartilage with Functional Properties.

@article{Huang2018OvercomingCI,
  title={Overcoming Challenges in Engineering Large, Scaffold-Free Neocartilage with Functional Properties.},
  author={Brian J. Huang and Wendy E. Brown and Thomas W Keown and Jerry C Hu and Kyriacos A. Athanasiou},
  journal={Tissue engineering. Part A},
  year={2018},
  volume={24 21-22},
  pages={
          1652-1662
        }
}
Although numerous cartilage engineering methods have been described, few report generation of constructs greater than 4 cm2, which is the typical lesion size considered for cell-based therapies. Furthermore, current cell-based therapies only target focal lesions, while treatment of large nonisolated lesions remains an area of great demand. The objective of this study was to scale up fabrication of self-assembled neocartilage from standard sizes of 0.2 cm2 to greater than 8 cm2. Passaged sheep… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 48 REFERENCES

Trends in the surgical treatment of articular cartilage lesions in the United States: an analysis of a large private-payer database over a period of 8 years.

  • Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association
  • 2014
VIEW 1 EXCERPT

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