Over-expression of the ribosomal protein L36a gene is associated with cellular proliferation in hepatocellular carcinoma.

@article{Kim2004OverexpressionOT,
  title={Over-expression of the ribosomal protein L36a gene is associated with cellular proliferation in hepatocellular carcinoma.},
  author={Jong-Hyun Kim and K G You and In Hee Kim and Baik Hwan Cho and Chan-Young Kim and Dae-Ghon Kim},
  journal={Hepatology},
  year={2004},
  volume={39 1},
  pages={129-38}
}
Using messenger RNA (mRNA) differential display, we identified a single complementary DNA (cDNA) fragment (HG23T1) that was over-expressed in a hepatocellular carcinoma (HCC) specimen. We cloned the full-length HG23T1 gene by the rapid amplification of cDNA end (RACE) polymerase chain reaction (PCR) method. It perfectly matched the gene encoding human ribosomal protein L36a (RPL36A also referred to as RPL44). RPL36A mRNA was preferentially over-expressed in 34 of 40 HCC cases (85%, P <.001) and… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 29 extracted citations

Similar Papers

Loading similar papers…