Over Expression of the Fatty Acid Synthase Is a Strong Predictor of Poor Prognosis and Contributes to Glucocorticoid Resistance in B-cell Acute Lymphoblastic Leukemia


Evolution of multiagent chemotherapy and independent risk factors have improved survival rates approximately 80% in children with acute lymphoblastic leukemia. Although, 20-30% of patients will be relapsed within the treatment process1. Outcome assessment based on risk factors could remarkably help to prevent relapse at this malignancy2. Hence, ALL patients… (More)


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