Over‐expression of human DNA polymerase lambda in E. coli and characterization of the recombinant enzyme

@article{Shimazaki2002OverexpressionOH,
  title={Over‐expression of human DNA polymerase lambda in E. coli and characterization of the recombinant enzyme},
  author={N. Shimazaki and Kenta Yoshida and Toshiko Kobayashi and S. Toji and K. Tamai and O. Koiwai},
  journal={Genes to Cells},
  year={2002},
  volume={7}
}
Background: DNA polymerase lambda (Pol λ) was recently identified as a new member of the family X of DNA polymerases in eukaryotic cells. Pol λ contains a nuclear localization signal (NLS), a BRCA1‐C terminal (BRCT) domain, a proline‐rich region, helix‐hairpin‐helix (HhH) and pol X motifs. Since the amino acid sequence for Pol λ shares a high degree of homology to Pol β, Pol λ is considered to have a similar enzymatic nature to Pol β. 
DNA polymerase lambda directly binds to proliferating cell nuclear antigen through its confined C‐terminal region
Cloning, expression and characterization of human tissue-specific DNA polymerase λ2
The Frameshift Infidelity of Human DNA Polymerase λ
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References

SHOWING 1-10 OF 47 REFERENCES
Identification and Characterization of Human DNA Polymerase β2, a DNA Polymerase β-Related Enzyme*
DNA polymerase lambda (Pol lambda), a novel eukaryotic DNA polymerase with a potential role in meiosis.
Identification and characterization of human DNA polymerase beta 2, a DNA polymerase beta -related enzyme.
Characterization of an African Swine Fever Virus 20-kDa DNA Polymerase Involved in DNA Repair*
Two novel human and mouse DNA polymerases of the polX family.
  • S Aoufouchi, E Flatter, +8 authors C A Reynaud
  • Biology, Medicine
  • Nucleic acids research
  • 2000
DNA polymerase mu (Pol μ), homologous to TdT, could act as a DNA mutator in eukaryotic cells
  • Orlando Domínguez, José F. Ruiz, +6 authors L. Blanco
  • Biology, Medicine
  • The EMBO journal
  • 2000
Studies of the domain structure of mammalian DNA polymerase beta. Identification of a discrete template binding domain.
...
1
2
3
4
5
...