Ovariectomy vs. hypofunction: their effects on rat mandibular bone.

  title={Ovariectomy vs. hypofunction: their effects on rat mandibular bone.},
  author={Simon C. F. Rawlinson and Alan Boyde and Graham R. Davis and Peter G T Howell and Francis J Hughes and Virginia J. Kingsmill},
  journal={Journal of dental research},
  volume={88 7},
Previous studies have suggested that the mandible may be more influenced by mechanical loading than by circulating hormone levels. We tested the hypothesis that hypofunction has a greater influence than ovariectomy on mandibular bone. Two-month-old rats were ovariectomized (OVX) or had maxillary molars removed from one side to induce unilateral mandibular hypofunction. Control animals remained untreated. After 5 months, animals were killed, and bones were assessed by micro-tomography (muCT… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 12 extracted citations

Estrogen deficiency reduces the dentinogenic capacity of rat lower incisors

Journal of Molecular Histology • 2013
View 1 Excerpt
Highly Influenced

Periodontal microstructure change and tooth movement pattern under different force magnitudes in ovariectomized rats: an in-vivo microcomputed tomography study.

American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics • 2013
View 1 Excerpt

Similar Papers

Loading similar papers…