Ovariectomy, social status, and atherosclerosis in cynomolgus monkeys.

  title={Ovariectomy, social status, and atherosclerosis in cynomolgus monkeys.},
  author={Michael R. Adams and Jay R. Kaplan and Thomas B. Clarkson and Donald Koritnik},
  volume={5 2},
Evidence is contradictory regarding the effects of natural or surgical menopause on "female protection" against coronary artery atherosclerosis. We evaluated atherosclerosis, plasma lipids, blood pressure, and carbohydrate tolerance in 21 ovariectomized and 23 intact female cynomolgus macaques fed a moderately atherogenic diet for 30 months. We also evaluated the influence of social dominance status, with particular emphasis on a possible relationship with ovarian endocrine function… CONTINUE READING


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