Ovarian transplantation between monozygotic twins discordant for premature ovarian failure.

@article{Silber2005OvarianTB,
  title={Ovarian transplantation between monozygotic twins discordant for premature ovarian failure.},
  author={Sherman J Silber and Kathleen M Lenahan and David L. Levine and Jorge Eduardo Pineda and Kim S Gorman and Michael J. Friez and E Cynda Crawford and Roger G. Gosden},
  journal={The New England journal of medicine},
  year={2005},
  volume={353 1},
  pages={58-63}
}
Monozygotic 24-year-old twins presented with discordant ovarian function. One had had premature ovarian failure at the age of 14 years, whereas her sister had normal ovaries and three naturally conceived children. After unsuccessful egg-donation therapy, the sterile twin received a transplant of ovarian cortical tissue from her sister by means of a minilaparotomy. Within three months after transplantation, the recipient's cycles resumed and serum gonadotropin levels fell to the normal range… CONTINUE READING

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