Ovarian susceptibility to benzo[a]pyrene: tissue burden of metabolites and DNA adducts in F-344 rats.

@article{Ramesh2010OvarianST,
  title={Ovarian susceptibility to benzo[a]pyrene: tissue burden of metabolites and DNA adducts in F-344 rats.},
  author={Aramandla Ramesh and Anthony E. Archibong and Mohammad S. Niaz},
  journal={Journal of toxicology and environmental health. Part A},
  year={2010},
  volume={73 23},
  pages={1611-25}
}
Exposure to environmental toxicants has been implicated as one of the causative factors for infertility in mammals. The objective of this study was to determine the amount of ingested benzo[a]pyrene (BaP), an environmental toxicant that reaches the reproductive tissues (internal dose) subsequent to a single acute exposure. Toward this end, the concentrations of BaP reactive metabolites and BaP-DNA adducts were measured throughout the course of BaP's residence in the body. Ten-week-old female… CONTINUE READING

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