Ovarian steroids: the good, the bad, and the signals that raise them.

@article{Jamnongjit2006OvarianST,
  title={Ovarian steroids: the good, the bad, and the signals that raise them.},
  author={Michelle Jamnongjit and Stephen R. Hammes},
  journal={Cell cycle},
  year={2006},
  volume={5 11},
  pages={1178-83}
}
Ovarian steroid production and subsequent local steroid-mediated signaling are critical for normal ovarian processes, including follicle growth, oocyte maturation, and ovulation. In contrast, elevated steroidogenesis and/or increased steroid signaling in the ovary can lead to profound ovarian pathology, such as polycystic ovarian syndrome, the leading cause of infertility in reproductive age women. Through the use of several in vitro and animal models, great strides have been made toward… CONTINUE READING