Ovarian hormones modulate cocaine-induced locomotor and stereotypic activity.

  title={Ovarian hormones modulate cocaine-induced locomotor and stereotypic activity.},
  author={Linda I. Perrotti and Scott J Russo and Holly Fletcher and Juliet Chin and Tennille Webb and Shirzad Jenab and Vanya Qui{\~n}ones-Jenab},
  journal={Annals of the New York Academy of Sciences},
Interactions between ovarian hormones and cocaine may underlie gender and estrous cycle differences in cocaine-induced behavioral and neurochemical alterations. The aim of this study was to further understand how ovarian hormones modulate cocaine-induced behavioral alterations. Ovariectomized rats received acute or chronic saline or cocaine (15 mg/kg i.p.) administration and were further subdivided into one of four hormone-treatment conditions: cholesterol (vehicle-control), estrogen… CONTINUE READING


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