Ovarian follicular development and the follicular fluid hormones and growth factors in normal women of advanced reproductive age.

@article{Klein1996OvarianFD,
  title={Ovarian follicular development and the follicular fluid hormones and growth factors in normal women of advanced reproductive age.},
  author={Nancy A. Klein and David Battaglia and Paul B. Miller and Emmett F. Branigan and Linda C. Giudice and Michael R. Soules},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1996},
  volume={81 5},
  pages={
          1946-51
        }
}
Reproductive aging in women (a physiological decline in the function of the hypothalamic-pituitary-ovarian axis) is an infrequently investigated and poorly understood biological phenomenon. Although menstrual irregularity and anovulation are known to precede the menopause, normal women in their fifth decade experience a profound decrease in fertility while still experiencing regular menstrual cycles. To further our understanding of the physiological changes associated with reproductive aging… CONTINUE READING
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