Ovarian estrogen receptor alpha and beta mRNA expression: impact of development and estrogen.

@article{Drummond1999OvarianER,
  title={Ovarian estrogen receptor alpha and beta mRNA expression: impact of development and estrogen.},
  author={Ann E. Drummond and Alan J Baillie and Jock K. Findlay},
  journal={Molecular and cellular endocrinology},
  year={1999},
  volume={149 1-2},
  pages={153-61}
}
We tested the hypothesis that ERalpha and ERbeta mRNAs in the rat ovary are regulated during the post-natal period and in immature rats in response to estrogen treatment. Total ovarian ERbeta mRNA was more abundant than ERalpha mRNA and expression of ERbeta increased between post-natal days 4 and 12, coinciding with advancing folliculogenesis and an increase in granulosa cell numbers. In contrast, ERalpha mRNA levels remained relatively constant during this period. In situ hybridisation studies… CONTINUE READING