Ovarian carcinoma cells in serous effusions show altered MMP-2 and TIMP-2 mRNA levels.

@article{Davidson2001OvarianCC,
  title={Ovarian carcinoma cells in serous effusions show altered MMP-2 and TIMP-2 mRNA levels.},
  author={Ben Davidson and Reuven Reich and Aasmund Berner and Vered Givant-Horwitz and Iris Goldberg and Bj\orn Risberg and Gunnar Balle Kristensen and Claes G{\"o}ran Trop{\'e} and Magne Bryne and Juri Kopolovic and Jahn Martin Nesland},
  journal={European journal of cancer},
  year={2001},
  volume={37 16},
  pages={2040-9}
}
The expression of matrix metalloproteinases (MMP) and their inhibitor TIMP-2 in serous effusions from patients with ovarian carcinoma and its association with clinico-pathological parameters were analysed. The findings in carcinoma cells in effusions were compared with corresponding primary and metastatic lesions. Sixty-six effusions and 96 tissue sections were stained for MMP-1, MMP-2 and MMP-9 applying immunohistochemistry (IHC) and analysed for MMP-2, MMP-9 and TIMP-2 expression using mRNA… CONTINUE READING
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