Ovarian cancer specific kallikrein profile in effusions.

  title={Ovarian cancer specific kallikrein profile in effusions.},
  author={Ie-ming Shih and Ritu Salani and Michael Fiegl and Tian-Li Wang and Antoninus R. Soosaipillai and Christian Marth and Elisabeth Mueller-Holzner and Gunther Gastl and Zhen Zhang and Eleftherios P Diamandis},
  journal={Gynecologic oncology},
  volume={105 2},
OBJECTIVE Kallikreins belong to the serine protease family and their roles as cancer associated markers have been proposed. However, a comprehensive and parallel analysis of different secreted kallikreins in ovarian cancer has not been performed. This study was undertaken to profile the secreted kallikreins in cancer effusion supernatants. METHODS We applied ELISA to measure the protein levels of nine kallikreins (4-8, 10, 11, 13, and 14) in a total of 221 effusion supernatants obtained from… CONTINUE READING
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