Ovarian cancer development and metastasis.

@article{Lengyel2010OvarianCD,
  title={Ovarian cancer development and metastasis.},
  author={Ernst Lengyel},
  journal={The American journal of pathology},
  year={2010},
  volume={177 3},
  pages={
          1053-64
        }
}
The biology of ovarian carcinoma differs from that of hematogenously metastasizing tumors because ovarian cancer cells primarily disseminate within the peritoneal cavity and are only superficially invasive. However, since the rapidly proliferating tumors compress visceral organs and are only temporarily chemosensitive, ovarian carcinoma is a deadly disease, with a cure rate of only 30%. There are a number of genetic and epigenetic changes that lead to ovarian carcinoma cell transformation… CONTINUE READING

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