Ovarian activin receptor subtype and follistatin gene expression in rats: reciprocal regulation by gonadotropins.

@article{Aloi1997OvarianAR,
  title={Ovarian activin receptor subtype and follistatin gene expression in rats: reciprocal regulation by gonadotropins.},
  author={J A Aloi and John C. Marshall and Mohammad Ajmal Yasin and Joan T Gilrain and Daniel J. Haisenleder and Alan C. Dalkin Bradley R. Javorsky Nelly Maybee Shetal Dalkin},
  journal={Biology of reproduction},
  year={1997},
  volume={56 6},
  pages={
          1565-9
        }
}
The production of activin, follistatin (FS), and inhibin, proteins present in the ovary and involved in mammalian reproduction, is regulated by gonadotropins and estradiol. We report here gonadotropin regulation of ovarian activin receptor (ActR) subtype and FS mRNAs. Expression of ActRI, ActRIIA, ActRIIB, and FS mRNA was measured on the afternoon of proestrus (1800 h) and the morning of estrus (0800 h). ActRI and ActIIA subtype mRNA concentrations fell by approximately 50% (p < 0.05) following… CONTINUE READING