Ovalbumin fused with diphtheria toxin protects mice from ovalbumin induced anaphylactic shock.

Abstract

For those with allergy, vaccination with a specific allergen has often been used as a major therapeutic measure. However, the universal application of this technique in clinics have been restricted due to its low success rates and the risk of active systemic anaphylactic shock (ASAS). In this regard, we constructed a fusion protein (OVA-DT), ovalbumin (OVA… (More)

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