Outwardly rectifying chloride channels in lymphocytes

@article{Garber1992OutwardlyRC,
  title={Outwardly rectifying chloride channels in lymphocytes},
  author={Sarah S. Garber},
  journal={The Journal of Membrane Biology},
  year={1992},
  volume={127},
  pages={49-56}
}
Outwardly rectifying Cl− channels in cultured human Jurkat T-lymphocytes were activated by excising a patch of membrane using the inside-out (i/o) patch-clamp configuration and holding at depolarized voltages for prolonged periods of time (1–6 min at +80 mV, 20°C). The single-channel current at +80 mV was 4.5 ± 0.3 pA and at −80 mV, it was 1.0 ± 0.4 pA. After activation, the probability of being open (P 0)for the lymphocyte channel was voltage independent. Activation of the Cl− channel in… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 30 references

Chloride ion transport in transformed human airway epithelial cells

A. L. Cozens, M. J. Yezzi, +4 authors D. C. Gruenert
Vitro (in press) • 1992
View 4 Excerpts
Highly Influenced

Separate CI- conductances activated by cAMP and C a - - in CI--secreting epithelial cells

W. H. Cliff, R. A. FrizzelI
Proc. Natl . Aead. Sci. USA 87:4956-4960 • 1990

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