Outpatient treatment of severe peripheral ischemia with intravenous intermittent low-dose iloprost. An open pilot study.


BACKGROUND Iloprost given in a standard dose regimen (0.5-2 ng/kg/min for 6 hours daily over 21-28 days) has proven to be effective and safe in hospitalized patients with critical limb ischemia. Major drawbacks of the standard regimen are the high frequency of side effects, the long duration of the daily infusion, and a hospital stay of 3 to 4 weeks… (More)


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