Outpatient antibiotic use in Europe and association with resistance: a cross-national database study

  title={Outpatient antibiotic use in Europe and association with resistance: a cross-national database study},
  author={H. Goossens and M. Ferech and R. V. Stichele and M. Elseviers and for the Esac Project Group},
  journal={The Lancet},
  • H. Goossens, M. Ferech, +2 authors for the Esac Project Group
  • Published 2005
  • Medicine
  • The Lancet
  • BACKGROUND Resistance to antibiotics is a major public-health problem and antibiotic use is being increasingly recognised as the main selective pressure driving this resistance. [...] Key MethodMETHODS We investigated outpatient antibiotic use in 26 countries in Europe that provided internationally comparable distribution or reimbursement data, between Jan 1, 1997, and Dec 31, 2002, by calculating the number of defined daily doses (DDD) per 1000 inhabitants per day, according to WHO anatomic therapeutic…Expand Abstract
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