Outer surface proteins E and F of Borrelia burgdorferi, the agent of Lyme disease.

@article{Lam1994OuterSP,
  title={Outer surface proteins E and F of Borrelia burgdorferi, the agent of Lyme disease.},
  author={T T Lam and Thi Minh Phuong Nguyen and Ruth R. Montgomery and Fred S. Kantor and Erol Fikrig and Richard A Flavell},
  journal={Infection and immunity},
  year={1994},
  volume={62 1},
  pages={290-8}
}
We report the cloning and characterization of two outer surface proteins (Osps), designated OspE and OspF, from strain N40 of Borrelia burgdorferi, the spirochetal agent of Lyme disease. The ospE and ospF genes are structurally arranged in tandem as one transcriptional unit under the control of a common promoter. The ospE gene, located at the 5' end of the operon, is 513 nucleotides in length and encodes a 171-amino-acid protein with a calculated molecular mass of 19.2 kDa. The ospF gene… CONTINUE READING

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