Outer membrane vesicles extracted from Neisseria meningitidis serogroup X for prevention of meningococcal disease in Africa.

@article{Acevedo2017OuterMV,
  title={Outer membrane vesicles extracted from Neisseria meningitidis serogroup X for prevention of meningococcal disease in Africa.},
  author={Reinaldo Acevedo and Caridad Zayas and Gunnstein Norheim and Sonsire Fern{\'a}ndez and B{\'a}rbara Cedr{\'e} and Yisabel Aranguren and Maribel Cuello and Yaimara Rodriguez and Humberto Gonz{\'a}lez and Aleida Mandiarote and Marylin P{\'e}rez and Maritza Hern{\'a}ndez and Mabel Hern{\'a}ndez-Cede{\~n}o and Domingo Iv{\'a}n Rodr{\'i}guez Gonz{\'a}lez and Sverre-Henning A Brorson and Einar Rosenqvist and Lisbeth Meyer Naess and Gro Tunheim and Daniel Cardoso and Luis Gerardo Fuenmayor Garc{\'i}a},
  journal={Pharmacological research},
  year={2017},
  volume={121},
  pages={194-201}
}
Meningococcal disease is caused mainly by serogroups A, B, C, Y, W of N. meningitidis. However, numerous cases of meningitis caused by serogroup X N. meningitidis (MenX) have recently been reported in several African countries. Currently, there are no licensed vaccines against this pathogen and most of the MenX cases have been caused by meningococci from clonal complex (c.c) 181. Detergent extracted meningococcal outer membrane vesicle (dOMV) vaccines have previously shown to be safe and… CONTINUE READING