Outer membrane phospholipase a dimer stability does not correlate to occluded surface area.

@article{Tan2008OuterMP,
  title={Outer membrane phospholipase a dimer stability does not correlate to occluded surface area.},
  author={Alexandra Ebie Tan and Karen G Fleming},
  journal={Biochemistry},
  year={2008},
  volume={47 46},
  pages={12095-103}
}
Despite the key roles of oligomeric membrane proteins (MPs) in many known cellular pathways, the principles governing their oligomer stability are not well-understood. Previous work with the alpha-helical MPs bacteriorhodopsin (bR) and glycophorin A (GpA) shows that lost buried surface area linearly correlated with perturbations in protein stability. Although this is a significant discovery, the predictive power of this correlation is limited by the data. Because both bR and GpA have alpha… CONTINUE READING