Outer membrane adhesion factor multivalent adhesion molecule 7 initiates host cell binding during infection by gram-negative pathogens.

Abstract

The initial binding of bacteria to host cells is crucial to the delivery of virulence factors and thus is a key determinant of the pathogen's success. We report a multivalent adhesion molecule (MAM) that enables a wide range of gram-negative pathogens to establish high-affinity binding to host cells during the early stages of infection. MAM7 binds to the… (More)
DOI: 10.1073/pnas.1102360108

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@article{Krachler2011OuterMA, title={Outer membrane adhesion factor multivalent adhesion molecule 7 initiates host cell binding during infection by gram-negative pathogens.}, author={Anne Marie Krachler and Hyeilin Ham and Kim Orth}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={2011}, volume={108 28}, pages={11614-9} }