Outcomes of salvage therapy for steroid-refractory acute severe ulcerative colitis: ciclosporin vs. infliximab.

@article{Croft2013OutcomesOS,
  title={Outcomes of salvage therapy for steroid-refractory acute severe ulcerative colitis: ciclosporin vs. infliximab.},
  author={Anthony Croft and Alex Walsh and James D Doecke and Robert Cooley and Melissa Howlett and Graham Radford-Smith},
  journal={Alimentary pharmacology & therapeutics},
  year={2013},
  volume={38 3},
  pages={294-302}
}
BACKGROUND Up to 40% of patients who present with acute severe ulcerative colitis (UC) fail to make an adequate response to intravenous corticosteroids. Ciclosporin or infliximab are currently employed as salvage therapy in this clinical scenario. AIM To compare clinical outcomes in patients treated with ciclosporin or infliximab in the setting of steroid-refractory acute severe UC. METHODS A prospective study of 83 consecutive presentations of steroid-refractory acute severe UC from 1999… CONTINUE READING

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