Outcomes of Therapeutic Penetrating Keratoplasty From a Tertiary Eye Care Centre in Northern India

@article{Sharma2014OutcomesOT,
  title={Outcomes of Therapeutic Penetrating Keratoplasty From a Tertiary Eye Care Centre in Northern India},
  author={N. Sharma and M. Jain and S. Sehra and P. Maharana and T. Agarwal and G. Satpathy and R. Vajpayee},
  journal={Cornea},
  year={2014},
  volume={33},
  pages={114–118}
}
Purpose: The aim was to study the outcomes and results of therapeutic penetrating keratoplasty (Th PK) at a tertiary eye care hospital in northern India. Methods: In this retrospective interventional study, a cohort of 506 eyes that underwent a Th PK for microbial keratitis was evaluated. Th PK was performed in cases of recalcitrant microbial keratitis with impending perforation (descemetocele formation) or perforation (>3 mm). Medical records were reviewed for demographic details, risk factors… Expand
Outcome of therapeutic penetrating keratoplasty in a tertiary eye care center in Nepal
TLDR
There is a high incidence of postoperative glaucoma, cataract, and graft failure in such a surgery, and bacterial ker atitis has a better outcome than fungal keratitis. Expand
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Therapeutic penetrating keratoplasty achieves anatomic success and it is a useful procedure for restoring a stable cornea in cases in which infection fails to heal or when the cornea perforates, and achieves corneal clarity and improves vision in most patients. Expand
To Study the Visual Outcome of Therapeutic Penetrating Keratoplasty in a Tertiary Care Center
Introduction: Corneal ulcer is the major cause of visual impairment and blindness. Lack of accessibility of eye care, delayed or inappropriate treatment, and microbes not responding to antimicrobialExpand
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TLDR
Therapeutic keratoplasty is an important procedure to save the eye and preserve vision in severe infective keratitis because there is a high incidence of postoperative glaucoma, cataract, and graft failure in such a surgery. Expand
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TLDR
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TLDR
TPK using glycerol-preserved corneas has a high rate of secondary glaucoma and recurrence of infection with unsatisfactory visual results and may be used as temporary emergency transplants in infectious keratitis when fresh cornea are unavailable to meet demands. Expand
Recurrence of Infection in Corneal Grafts After Therapeutic Penetrating Keratoplasty for Microbial Keratitis.
TLDR
Fungal etiology, retro-iris exudates, coexisting endophthalmitis, and larger grafts were susceptible to recurrence and TPK remains an effective treatment in severe nonresponsive keratitis. Expand
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TLDR
Indications and complications significantly affect the anatomical, therapeutic, and functional outcome of therapeutic penetrating keratoplasty, and ultimate graft clarity showed significant impact on the anatomical outcome. Expand
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Therapeutic keratoplasty was an effective procedure in managing refractory infectious keratitis and prompt and appropriate surgery would result in fewer complications and better outcomes. Expand
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Therapeutic keratoplasty including PK and patch grafting is an effective surgical procedure in patients with severe corneal melting or perforation due to varying aetiologies and restores the globe integrity also provides visual improvement. Expand
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The prognosis of therapeutic penetrating keratoplasty in herpetic eye disease can only be improved with proper postoperative care and optimal management of immunologic and virologic complications. Expand
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The results confirm that therapeutic penetrating keratoplasty for infections is successful in restoring anatomic integrity in most eyes. Expand
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Therapeutic PK is effective in the management of the eye with active uncontrolled infection or perforation from corneal disease and cured the disease in all bacterial keratitis cases. Expand
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If penetrating keratoplasties were performed for an infectious corneal perforation, grafts had a better chance to remain clear if surgery could be delayed and delaying surgery for at least 3 months significantly improved the chances for graft success. Expand
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TLDR
KP is an effective treatment approach for fungal keratitis and effective, preventive and therapeutic measures can improve the prognosis, and there is a higher incidence of complications in large-diameter PKP forFungal Keratitis. Expand
Outcomes of Treatment of Fungal Keratitis at the University of Iowa Hospitals and Clinics: A 10-Year Retrospective Analysis
TLDR
A high microbiological cure rate can be achieved in eyes with fungal keratitis; however, TKP is often needed to achieve this objective, and multiple keratoplasty procedures may be required. Expand
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Appropriate initial treatment is most critical in the course of serious corneal ulcers, and aggressive, broad-spectrum antibiotic coverage is advocated. Expand
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TLDR
Penetrating keratoplasty was performed as an emergency procedure in 52 eyes which had perforated from acute microbial keratitis and in a further 11 where perforation had not yet occurred, resulting in a better five year survival and significantly better visual acuities. Expand
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The unexpected finding of a better prognosis for male donor buttons might suggest the preferred use of male donors in patients suffering from microbial keratitis, but the observation needs further documentation. Expand
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