Outcomes of Tacrolimus Therapy in Adults With Refractory Membranous Nephrotic Syndrome: A Prospective, Multicenter Clinical Trial

@article{Chen2013OutcomesOT,
  title={Outcomes of Tacrolimus Therapy in Adults With Refractory Membranous Nephrotic Syndrome: A Prospective, Multicenter Clinical Trial},
  author={W. Chen and Qinghua Liu and Yunhua Liao and Z. Yang and J. Chen and Junzhou Fu and J. Zhang and Yaozhong Kong and P. Fu and T. Lou and Z. Liu and Yulian Ji and Z. Li and X. Yu},
  journal={The American Journal of the Medical Sciences},
  year={2013},
  volume={345},
  pages={81–87}
}
  • W. Chen, Qinghua Liu, +11 authors X. Yu
  • Published 2013
  • Medicine
  • The American Journal of the Medical Sciences
  • Introduction:The treatment of adult refractory idiopathic membranous nephropathy with steroid and other immunosuppressant-resistant nephrotic syndrome can be a significant challenge. The authors investigated the efficacy and safety of tacrolimus (TAC) as a promising regimen. Methods:A prospective, multicenter trial was conducted in 9 nephrology centers from 2006 to 2008. Fourteen patients were enrolled. In conjunction with prednisone, TAC was started at 0.05 mg/kg/d, titrated to achieve a… CONTINUE READING
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