Outcomes and prognostic factors in recurrent glioma patients enrolled onto phase II clinical trials.

@article{Wong1999OutcomesAP,
  title={Outcomes and prognostic factors in recurrent glioma patients enrolled onto phase II clinical trials.},
  author={Eric T. Wong and Kenneth R. Hess and Mary Jo Gleason and Kurt A. Jaeckle and Athanassios P. Kyritsis and Michael D. Prados and V. A. Levin and W. K. Alfred Yung},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={1999},
  volume={17 8},
  pages={2572-8}
}
PURPOSE To determine aggregate outcomes and prognostic covariates in patients with recurrent glioma enrolled onto phase II chemotherapy trials. PATIENTS AND METHODS Patients from eight consecutive phase II trials included 225 with recurrent glioblastoma multiforme (GBM) and 150 with recurrent anaplastic astrocytoma (AA). Their median age was 45 years (range, 15 to 82 years) and their median Karnofsky performance score was 80 (range, 60 to 100). Prognostic covariates were analyzed with respect… CONTINUE READING
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