Outcome of unrelated donor bone marrow transplantation in 40 children with Hurler syndrome.

@article{Peters1996OutcomeOU,
  title={Outcome of unrelated donor bone marrow transplantation in 40 children with Hurler syndrome.},
  author={Christina Peters and Michael Balthazor and Elsa G. Shapiro and Roberta J King and Craig R. Kollman and Janet Hegland and Jean P Henslee-Downey and Michael e. Trigg and Morton J Cowan and Jean E. Sanders and N Bunin and Herbert Weinstein and Carl Lenarsky and Peter Falk and R Harris and Timothy Bowen and Thomas Emrys Williams and Guy H. Grayson and Peter Warkentin and Leonard Sender and V A Cool and Marka R. Crittenden and Sheryl Packman and Petek Kaplan and Lawrence A Lockman and Jessica N Anderson and William Krivit and K Dusenbery and J Wagner},
  journal={Blood},
  year={1996},
  volume={87 11},
  pages={4894-902}
}
Long-term survival and improved neuropsychological function have occurred in selected children with Hurler syndrome (MPS I H) after successful engraftment with genotypically matched sibling bone marrow transplantation (BMT). However, because few children have HLA-identical siblings, the feasibility of unrelated donor (URD) BMT as a vehicle for adoptive enzyme therapy was evaluated in this retrospective study. Forty consecutive children (median, 1.7 years; range, 0.9 to 3.2 years) with MPS I H… CONTINUE READING