Outcome of ulcerative colitis after treatment with transdermal nicotine.

  title={Outcome of ulcerative colitis after treatment with transdermal nicotine.},
  author={Mario Guslandi and Alberto Tittobello},
  journal={European journal of gastroenterology & hepatology},
  volume={10 6},
OBJECTIVE Transdermal nicotine appears to be of benefit in the short-term treatment of patients with ulcerative colitis. The aim of this study was to determine its long-term effects. DESIGN A randomized, comparative study. PATIENTS AND METHODS Patients with mild to moderate clinical relapses of left-sided ulcerative colitis during maintenance treatment with mesalamine 1 g b.i.d. were allocated to an additional treatment with either transdermal nicotine or prednisone for 5 weeks. The first… CONTINUE READING

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Response to Dr. Guslandi

American Journal of Gastroenterology • 1999

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