Outcome of pregnancies when fathers are treated with 6-mercaptopurine for inflammatory bowel disease

@article{Rajapakse2000OutcomeOP,
  title={Outcome of pregnancies when fathers are treated with 6-mercaptopurine for inflammatory bowel disease},
  author={Ramona O. Rajapakse and Burton I. Korelitz and Jusuf Zlatanic and Peter J Baiocco and Gilbert W. Gleim},
  journal={American Journal of Gastroenterology},
  year={2000},
  volume={95},
  pages={684-688}
}
OBJECTIVE:The outcomes of pregnancies after maternal use of 6-mercaptopurine (6-MP) for inflammatory bowel disease (IBD) during pregnancy have been reported, but data are lacking for outcomes when the fathers use this drug.METHODS:Subjects were male patients with IBD seen at one center between 1970 and 1997. Patients and their wives were interviewed. Group 1 comprised pregnancies fathered by men who were taking 6-MP. This group was further subdivided into those conceived within 3 months of 6-MP… CONTINUE READING

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