Outcome of plasma exchange therapy in thrombotic microangiopathy after renal transplantation.

@article{Karthikeyan2003OutcomeOP,
  title={Outcome of plasma exchange therapy in thrombotic microangiopathy after renal transplantation.},
  author={Vanji Karthikeyan and Raviprasenna Parasuraman and Veena V Shah and Edgard Vera and K. K. Venkat},
  journal={American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons},
  year={2003},
  volume={3 10},
  pages={1289-94}
}
Thrombotic microangiopathy (TMA) in renal transplant recipients is commonly associated with calcineurin inhibitors (CNIs), though several factors such as vascular rejection, viral infections and other drugs may play a contributory role. We report a series of 29 patients with TMA, all of whom were on CNIs. Though plasma exchange (PEx) is widely used to treat TMA, therapeutic guidelines are not well defined. All our patients were treated with PEx and discontinuation of CNIs. Thrombotic… CONTINUE READING
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