Outcome of nicotine replacement therapy in patients admitted to ICU: a randomized controlled double-blind prospective pilot study.

@article{Pathak2013OutcomeON,
  title={Outcome of nicotine replacement therapy in patients admitted to ICU: a randomized controlled double-blind prospective pilot study.},
  author={Vikas Pathak and Iliana Samara Hurtado Rendon and Roxana E. Lupu and Nancy Tactuk and Toyosi Olutade and Carolyn G Durham and Richard Stumacher},
  journal={Respiratory care},
  year={2013},
  volume={58 10},
  pages={1625-9}
}
BACKGROUND The effect of nicotine withdrawal in smokers admitted to the ICU is not well understood, so the role of nicotine replacement therapy (NRT) in those patients is controversial. OBJECTIVE To determine whether NRT in ICU patients affects the need for sedatives/analgesics, ventilator days, and ICU stay. METHODS In a 20-bed ICU, 40 subjects were randomized to either a 21 mg nicotine patch or a placebo nicotine patch daily until either ICU discharge, transfer to a medical floor, or 10… CONTINUE READING
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