Outcome of conservatively managed early-onset breast cancer by BRCA1/2 status.

  title={Outcome of conservatively managed early-onset breast cancer by BRCA1/2 status.},
  author={Bruce G. Haffty and Elizabeth Harrold and Atif J. Khan and Pradip M Pathare and Tanya E Smith and Bruce C. Turner and Peter M. Glazer and Barbara J Ward and Daryl Carter and Ellen T. Matloff and A. Bale and Mayra Alvarez-Franco},
  volume={359 9316},
BACKGROUND Management of early-stage breast cancer in young women with mutations in BRCA1 or BRCA2 remains controversial. This study assessed the long-term risks of ipsilateral and contralateral breast cancer in a cohort of young women who underwent breast-conserving surgery followed by radiotherapy. METHODS Between 1975 and 1998, 290 women with breast cancer diagnosed at age 42 years or younger underwent lumpectomy followed by radiotherapy at our hospital. We recruited 127 of these women for… CONTINUE READING
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