Outcome of children and adolescents with a second or third relapse of acute lymphoblastic leukemia (ALL): a population-based analysis of the Austrian ALL-BFM (Berlin-Frankfurt-Münster) study group.

@article{Reismller2013OutcomeOC,
  title={Outcome of children and adolescents with a second or third relapse of acute lymphoblastic leukemia (ALL): a population-based analysis of the Austrian ALL-BFM (Berlin-Frankfurt-M{\"u}nster) study group.},
  author={Bettina Reism{\"u}ller and C Peters and Michael Dworzak and Ulrike Poetschger and Christian Urban and Bernhard Meister and Klaus Schmitt and Karin Ute Dieckmann and Helmut Gadner and Andishe Attarbaschi and Georg Mann},
  journal={Journal of pediatric hematology/oncology},
  year={2013},
  volume={35 5},
  pages={e200-4}
}
We analyzed outcome of a population-based cohort of 74 children with second and third acute lymphoblastic leukemia (ALL) relapse and aimed to identify prognostic factors. Duration of previous remission and site of relapse appeared of prognostic relevance as patients with a second remission duration >1.5 years and isolated extramedullary relapse did better. Neither patient with a second bone marrow relapse who underwent previous allogeneic transplantation nor patients with T-cell ALL survived… CONTINUE READING

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Bone MarrowIs primary anatomic site of diseaseChronic Lymphocytic Leukemia
Neither patient with a second bone marrow relapse who underwent previous allogeneic transplantation nor patients with T - cell ALL survived .
Neither patient with a second bone marrow relapse who underwent previous allogeneic transplantation nor patients with T - cell ALL survived .
Neither patient with a second bone marrow relapse who underwent previous allogeneic transplantation nor patients with T - cell ALL survived .
Neither patient with a second bone marrow relapse who underwent previous allogeneic transplantation nor patients with T - cell ALL survived .
Stem cell transplantation seemed to be the only curative option for systemic relapse of B - cell precursor
Stem cell transplantation seemed to be the only curative option for systemic relapse of B - cell precursor
Stem cell transplantation seemed to be the only curative option for systemic relapse of B - cell precursor
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