Outcome of cephalosporin treatment for serious infections due to apparently susceptible organisms producing extended-spectrum beta-lactamases: implications for the clinical microbiology laboratory.

Abstract

Although extended-spectrum beta-lactamases (ESBLs) hydrolyze cephalosporin antibiotics, some ESBL-producing organisms are not resistant to all cephalosporins when tested in vitro. Some authors have suggested that screening klebsiellae or Escherichia coli for ESBL production is not clinically necessary, and when most recently surveyed the majority of… (More)

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@article{Paterson2001OutcomeOC, title={Outcome of cephalosporin treatment for serious infections due to apparently susceptible organisms producing extended-spectrum beta-lactamases: implications for the clinical microbiology laboratory.}, author={David L Paterson and Wen - Chien Ko and Anne von Gottberg and Jos{\'e} Mar{\'i}a Casellas and Lutfiye Mulazimoglu and K. P. Klugman and Robert A. Bonomo and Louis B. Rice and Joseph G. McCormack and Victor L. Yu}, journal={Journal of clinical microbiology}, year={2001}, volume={39 6}, pages={2206-12} }