Outcome of anti-HBe positive chronic hepatitis B in alpha-interferon treated and untreated patients: a long term cohort study.

@article{Brunetto2002OutcomeOA,
  title={Outcome of anti-HBe positive chronic hepatitis B in alpha-interferon treated and untreated patients: a long term cohort study.},
  author={Maurizia Rossana Brunetto and Filippo Oliveri and Barbara Agata Coco and Gioacchino Leandro and Piero Colombatto and Juliana Monti Gorin and Ferruccio Bonino},
  journal={Journal of hepatology},
  year={2002},
  volume={36 2},
  pages={263-70}
}
BACKGROUND/AIMS We studied the influence of biochemical and virologic patterns and interferon on the outcome of anti-HBe positive chronic hepatitis B in 164 (103 treated) consecutive patients, followed-up prospectively for a mean of 6 years (21 months-12 years). METHODS Histology, biochemical and virologic profiles were characterized by monthly monitoring during the first 12 months of follow-up. Thereafter patients underwent blood and clinical controls every 4 and 6 months, respectively… CONTINUE READING

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