Outcome of adrenal vein sampling performed during concurrent mineralocorticoid receptor antagonist therapy.

Abstract

CONTEXT Pharmacological inhibition of mineralocorticoid receptor (MR) signaling in patients with primary aldosteronism (PA) reestablishes aldosterone synthesis by nondiseased zona glomerulosa cells through activation of the renin-angiotensin-aldosterone system. In this context, current guidelines recommend discontinuing MR blockade for diagnostic procedures… (More)
DOI: 10.1210/jc.2014-2788

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