Outcome of acute idiosyncratic drug-induced liver injury: Long-term follow-up in a hepatotoxicity registry.

@article{Andrade2006OutcomeOA,
  title={Outcome of acute idiosyncratic drug-induced liver injury: Long-term follow-up in a hepatotoxicity registry.},
  author={Raul Andrade and Maria Isabel Lucena and Neil Kaplowitz and Beatriz Garc{\'i}a-Muņoz and Yolanda Borraz and Ketevan Pachkoria and Miren Garc{\'i}a-Cort{\'e}s and M A Carmen Fernandez and Gloria Pelaez and Luis Rodrigo and Jose Antonio Sanchez Duran and J de S Costa and Ram{\'o}n Planas and Anabel Barriocanal and Carlos Guarner and Manuel Romero-G{\'o}mez and Teresa Muņoz-Yag{\"u}e and Javier Salmer{\'o}n and Ram{\'o}n Hidalgo},
  journal={Hepatology},
  year={2006},
  volume={44 6},
  pages={1581-8}
}
A chronic adverse reaction may occur in some instances of drug-induced liver injury (DILI), even despite drug cessation. In our study, we obtained records from a Spanish registry and evaluated cases of DILI with biochemical evidence of long-term damage. Chronic outcome was defined as a persistent biochemical abnormality of hepatocellular pattern of damage more than 3 months after drug withdrawal or more than 6 months after cholestatic/mixed damage. Data on 28 patients with a chronic clinical… CONTINUE READING
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Acute liver failure in Sweden: etiology and prognosis [Abstract

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