Outcome measures for clinical trials in paediatric IBD: an evidence-based, expert-driven practical statement paper of the paediatric ECCO committee.

@article{Ruemmele2015OutcomeMF,
  title={Outcome measures for clinical trials in paediatric IBD: an evidence-based, expert-driven practical statement paper of the paediatric ECCO committee.},
  author={Frank M. Ruemmele and Jeffrey S. Hyams and Anthony R Otley and Anne Marie Griffiths and K-L Kolho and Jorge Dias and Arie Levine and Johanna C Escher and J. A. J. M. Taminiau and G{\'a}bor G{\'a}bor Veres and J. F. Colombel and S{\'e}verine Vermeire and David C. Wilson and Dan Turner},
  journal={Gut},
  year={2015},
  volume={64 3},
  pages={438-46}
}
OBJECTIVE Although paediatric-onset IBD is becoming more common, few medications have a registered paediatric indication. There are multiple hurdles to performing clinical trials in children, emphasising the importance of choosing an appropriate outcome measure, which can facilitate enrolment, and thereby also drug approval. The aim of this consensus statement is to highlight paediatric specific issues and key factors critical for the optimal conduct of paediatric IBD trials. DESIGN The… CONTINUE READING
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Agreement among central readers in the evaluation of endoscopic disease activity in Crohn ’ s disease

  • R Khanna, G Zou, G D’Haens
  • J Crohn ’ s Colitis
  • 2014

Correlation between the endoscopic and histologic score in assessing the activity of ulcerative colitis

  • T Bessissow, B Lemmens, M Ferrante
  • In fl amm Bowel Dis
  • 2013

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