Outcome for children and young people with Early T-cell precursor acute lymphoblastic leukaemia treated on a contemporary protocol, UKALL 2003.

@article{Patrick2014OutcomeFC,
  title={Outcome for children and young people with Early T-cell precursor acute lymphoblastic leukaemia treated on a contemporary protocol, UKALL 2003.},
  author={Katharine L Patrick and Rachel Wade and Nick Goulden and Chris Mitchell and Anthony V Moorman and Clare Rowntree and Sarah. F. Jenkinson and Rachael Hough and Ajay J. Vora},
  journal={British journal of haematology},
  year={2014},
  volume={166 3},
  pages={421-4}
}
We investigated the outcome for children and young people with Early T-precursor acute lymphoblastic leukaemia (ETP-ALL), a recently described poor prognosis sub-group of T-ALL, treated on a contemporary protocol, UKALL 2003. After a median follow-up of 4 years and 10 months, the ETP sub-group, representing 16% of T-ALL patients, had non-significantly inferior 5-year event-free survival (76·7% vs. 84·6%, P = 0·2) and overall survival (82·4% vs. 90·9%, P = 0·1), and a higher relapse rate (18·6… CONTINUE READING

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