Outcome assessment in clinical trials of fracture-healing.

  title={Outcome assessment in clinical trials of fracture-healing.},
  author={Saam Morshed and Luis A. Corrales and Harry Genant and Theodore Miclau},
  journal={The Journal of bone and joint surgery. American volume},
  volume={90 Suppl 1},
Although there are numerous methods for defining fracture-healing in clinical studies, no consensus exists regarding the most valid and reliable manner for assessing union or for determining which outcomes are most important. This article summarizes and describes methods for the clinical assessment of fracture-healing and reports results from a systematic review of prevalent definitions currently used in published clinical studies. Conventional radiography and ad hoc clinical definitions… CONTINUE READING
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