Outcome assessment and clinical improvement in panic disorder: evidence from a randomized controlled trial of fluoxetine and placebo. The Fluoxetine Panic Disorder Study Group.

@article{Michelson1998OutcomeAA,
  title={Outcome assessment and clinical improvement in panic disorder: evidence from a randomized controlled trial of fluoxetine and placebo. The Fluoxetine Panic Disorder Study Group.},
  author={David Michelson and Robert Bruce Lydiard and Mark H. Pollack and Roy N. Tamura and Sharon L Hoog and R. G. Tepner and Mark A. Demitrack and Gary D. Tollefson},
  journal={The American journal of psychiatry},
  year={1998},
  volume={155 11},
  pages={
          1570-7
        }
}
OBJECTIVE Although panic attacks account for only a portion of the morbidity of panic disorder and panic attack frequency assessments are unreliable, studies of drug efficacy in panic disorder have generally used reduction in panic attack frequency as the primary measure of improvement. The authors studied the efficacy of fluoxetine treatment in panic disorder and measured the relative contributions of changes in symptoms to overall improvement. METHOD Patients with a diagnosis of panic… CONTINUE READING

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