Outcome after neoadjuvant chemotherapy in elderly breast cancer patients – a pooled analysis of individual patient data from eight prospectively randomized controlled trials

@inproceedings{Waldenfels2015OutcomeAN,
  title={Outcome after neoadjuvant chemotherapy in elderly breast cancer patients – a pooled analysis of individual patient data from eight prospectively randomized controlled trials},
  author={Gabriel von Waldenfels and Sibylle Loibl and Jenny Furlanetto and Anna Machleidt and Bianca Lederer and Carsten Denkert and Claus Hanusch and Sherko K{\"u}mmel and Gunter von Minckwitz and Andreas Schneeweiss and Michael Untch and Kerstin Rhiem and Peter A. Fasching and Jens Uwe Blohmer},
  booktitle={Breast Cancer Research and Treatment},
  year={2015}
}
Young women with breast cancer (BC) have a worse survival partly due to more aggressive tumor characteristics; however, their response to chemotherapy seems better. We investigated to what extent the prognostic factor pathological complete remission (pCR) after neoadjuvant chemotherapy is applicable to young women. 8949 patients with primary BC and follow-up from eight German neoadjuvant trials were included. A subgroup of 1453 patients <40 years was compared with women aged 40–49 and ≥50 years… CONTINUE READING