Out of the ER--outfitters, escorts and guides.

  title={Out of the ER--outfitters, escorts and guides.},
  author={Johannes M Herrmann and Per N Malkus and Randy Schekman},
  journal={Trends in cell biology},
  volume={9 1},
The endoplasmic reticulum (ER) contains a variety of specialized proteins that interact with secretory proteins and facilitate their uptake into transport vesicles destined for the Golgi apparatus. These accessory proteins might induce and/or stabilize a conformation that is required for secretion competence or they might be directly involved in the sorting and uptake of secretory proteins into Golgi-bound vesicles. Recent efforts have aimed to identify and characterize the role of several of… CONTINUE READING

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