Out-of-hospital hypertonic resuscitation after traumatic hypovolemic shock: a randomized, placebo controlled trial.

@article{Bulger2011OutofhospitalHR,
  title={Out-of-hospital hypertonic resuscitation after traumatic hypovolemic shock: a randomized, placebo controlled trial.},
  author={Eileen M. Bulger and Susanne May and Jeffery D Kerby and Scott S. Emerson and Ian G Stiell and Martin Schreiber and Karen J. Brasel and Samuel A. Tisherman and Raul Coimbra and Sandro Rizoli and Joseph P. Minei and John Hata and George S Sopko and David C. Evans and David Butler Hoyt},
  journal={Annals of surgery},
  year={2011},
  volume={253 3},
  pages={
          431-41
        }
}
OBJECTIVE To determine whether out-of-hospital administration of hypertonic fluids would improve survival after severe injury with hemorrhagic shock. BACKGROUND Hypertonic fluids have potential benefit in the resuscitation of severely injured patients because of rapid restoration of tissue perfusion, with a smaller volume, and modulation of the inflammatory response, to reduce subsequent organ injury. METHODS Multicenter, randomized, blinded clinical trial, May 2006 to August 2008, 114… CONTINUE READING
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